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Some studies have indicated a protective role of estradiol in mitochondria, showing that it can inhibit the passage of ROS into mitochondria as well as preventing mitochondrial collapse and increasing the rate of ATP synthesis (Wang et al., 2003

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Nature Medicine , 25(7), 1231-1241

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The possibility of bruising increases if youre taking a medication or supplement that thins the blood like warfarin, Coumadin, aspirin, fish oil, Ginkgo Biloba, or garlic

In addition, the oxidants may also originate from cytosolic enzyme systems, e.g., NADPH oxidases, and from exogenous triggers such as ionizing radiation and chemotherapeutics