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doi: 10.3390/medsci6040116 8 SinghAVishwakarmaVSinghalB

10.1038/gim.2017.83 413 Zarzuelo-RomeroM

Fer-1 suffers from poor water solubility, which severely limits its bioavailability and hinders its therapeutic potential ( Despite its potent antioxidant properties, the clinical utility of GB is hindered by poor bioavailability and inefficient delivery to target tissues, limiting its therapeutic efficacy ( While high-dose -tocopherol supplementation may exert therapeutic effects in specific contexts, the current evidence on the safety profile of high-dose -tocopherol supplementation is still inconclusive