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A dedicated study coordinator is assigned, and participants will be provided with direct contact information to address any questions or concerns and to facilitate appointment scheduling

This has already been postulated and confirmed in other studies: a PCT increase in 24 hours in the critically-ill patient has been associated with an increase of in-hospital mortality at 90 days 7

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Funding The SCALE trial program and the medical writing/editorial support for this paper were funded by Novo Nordisk A/S

185,186,187 When mast cells in the gastrointestinal tract are deficient in antitumor-associated G protein-coupled receptor X2 (MRGPRX2), E