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This could potentially result in the overestimation of GSSG and thus lower GSH:GSSG values

And stopping them

Polymorphisms and a rare missense mutation that impair CaMKK2 function are associated with bipolar disorder Whole exome sequencing and genetic association studies have uncovered a link between bipolar disorder and loss-of-function polymorphisms and mutations in human CAMKK2

Jones, Ghassemzadeh 2018)

To formally test whether mitochondrial GSH depletion is necessary for cell proliferation, we would need to restore mitochondrial glutathione levels upon SLC25A39/40 loss