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casei, Shirota was reported to inhibit the occurrence of autoimmune diseases by changing the cytokines produced by antigen-presenting cells, thereby inhibiting the differentiation of lymphocytes into specific subsets of effector T cells (Snchez et al., 2011)

Threonine residue is reported to induce aggregation in proteins and supports the beta-sheet structures by unique effects on interaction with its surroundings including the consequent 3D structure, stability and dynamic behavior, in contrast to alanine which supports formation of - helices