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(2023), the analgesic effect of a single intrathecal dose of AST in mice during 7 days was shown to be mediated through inhibiting mitogen-activated protein kinase and activating nuclear factor erythroid 2related factor 2

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Thus, disruption of mitochondrial iron homeostasis may amplify oxidative injury to mitochondrial proteins, lipids, and DNA, compromise ATP generation, and ultimately trigger energy stress that converges on ferroptotic cell death

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During high-light stress, mitochondria facilitate the re-oxidation of excess reducing equivalents produced in plastids, thereby preventing over-reduction of the plastidic electron transport chain and limiting ROS overproduction

The gene transcription factor cyclic AMP-responsive element binding protein: role in positive and negative affective states of alcohol addiction