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"Injections are the preferred treatment for patients unable to absorb vitamin B12, such as patients with autoimmune-related anemia or pernicious anemia, or history of gastrectomy, which means partial removal of the stomach, or a history of bariatric surgery," Levine told InStyle

Inositol, akin to a B vitamin, aids in the distribution of fat and in maintaining a healthy cell structure, while Choline supports liver function and fat excretion

A seminal cost analysis published in Canadian Family Physician (2001) projected that switching patients from intramuscular B12 injections to oral supplements could save between $2.9 million and $17.6 million depending on the population studied with one Ontario analysis estimating $14.5 million in savings for 110,000 elderly patients

To date, the most promising clinical trial focuses on the progressive muscle disease mitochondrial myopathy 244

Peptides are typically safe when administered by a licensed medical professional

Methylmalonic acid is especially helpful when standard B12 levels appear falsely elevated but symptoms remain