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KEAP1 is a sensor protein that detects environmental pollutants, leading to activation of the transcription factor NRF2

The antitumorigenic effect of TLR is typically attributed to the stimulation of antitumor immunity through the activation of dendritic cells

[PubMed] [Google Scholar] 20.Sagiv A, Biran A, Yon M, Simon J, Lowe SW, & Krizhanovsky V

The authors, with the aim of mimicking physiological methanol toxicity in humans, and investigating the role of aspartame-derived methanol, investigated the effects of aspartame in conditions of folate deficiency (by pretreatment with methotrexate) in rodents

The anticonvulsant, phenytoin, has been shown to inhibit the intestinal absorption of folate, and several studies have associated decreased folate status with long-term use of the anticonvulsants, phenytoin, phenobarbital, and primidone (214)

Samples were diluted 100-fold, applied to copper grids, and stained using uranyl acetate at a concentration of 2% w/v