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Main conclusions: GHK-Cu acts via 6 main mechanisms (described above) The endogenous decrease with age is documented in various populations Topical applications in dermatology are the best validated Antimicrobial effect , GHK-Cu also has a mild antibacterial profile The safety profile is excellent, no toxic doses were reached in animal studies Why it matters: This review became a reference source for the dermatological and cosmetic research community

All authors reviewed and approved the final manuscript

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Evoy KE, Covvey JR, Peckham AM, Ochs L, Hultgren KE

Why trials are inconclusive for weight Many studies mix populations, use different doses, or add other supplements

These molecules work at a cellular level to stimulate repair and regenerate skin structure, improving skin elasticity, hydration, and tone