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In still another embodiment, an ADC of the invention specifically binds more then one Eph receptor

Views of aging and senescence frequently highlight a deterioration in mitochondrial health and function with age, and investigations of NAD+ depletion and the associated oxidative stress and damage corroborate these theories (1-2)

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Although cholesterol was not directly manipulated in this study, our findings are consistent with a model in which cholesterol delivery via HDL and sequestration into lipid droplets act in parallel with triglyceride storage to suppress peroxidative stress and promote ferroptosis resistance