chac1 glutathione L-2-Hydroxyglutarate sensitizes ferroptosis through ATF3/CHAC1-mediated degradation in hepatocellular carcinoma TRIB3 increases cell resistance to

TRIB3 increases cell resistance to arsenite toxicity by limiting the expression of the glutathione degrading enzyme CHAC1 ScienceDirect Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF CRE Regulatory Element* Journal of Biological Chemistry Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF CRE Regulatory Element ScienceDirect BACH1CHAC1Glutathione Axis Aggravates Myocardial IschemiaReperfusion Injury by Enhancing Ferroptosis and Oxidative Stress Frontiers The strategic breakdown: CHAC enzymes as regulators of glutathione homeostasis and disease implications Dysregulated lipids homeostasis disrupts CHAC1 mediated ferroptosis driving fibroblast growth factor receptor tyrosine kinase inhibitor AZD4547 resistance in gastric cancer ScienceDirect

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