Auxiliary subunits: essential components of the voltage-gated calcium channel complex
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Gut Healing to Restore Immune Function Mold toxins can disrupt gut health, leading to leaky gut syndrome, food sensitivities, and weakened immunity

Abbreviations ASX: Astaxanthin ADI: Acceptable daily intake ALP: Alkaline phosphatase AST: Aspartate aminotransferase CNS: Central nervous system CIAKI: Contrast-induced acute kidney injury COX-2: Cyclooxygenase DM: Diabetes mellitus DPPH: 2:2-Diphenly-1-picrylhydrazyl EPA: Eicosapentaenoic acid EFSA: European food safety authority FPE: Food processing effluent GGPS: Geranylgeranyl pyrophosphate synthase Ig: Immunoglobulin iNOS: Inducible nitrogen oxygen species IL: Interleukin IPP: Isopentyl pyrophosphate MMPs: Matrix metalloproteinases MVA: Mevalonate pathway MAE: Microwave-assisted extraction NDES: Natural deep eutectic solvents MEP: Non-mevalonate pathway NLRP3: Nucleotide-binding oligomerization domain-like receptor protein 3 PCL: Polycaprolactone PDS: Phytoene desaturase PGE2: Prostaglandin E2 PLE: Pressurized liquid extraction ROS: Reactive oxygen species SFE: Supercritical fluid extraction SNEDDS: Self-nano-emulsifying drug delivery systems TAGs: Triacylglycerols TNF-: Tumor necrosis factor-alpha UAE: Ultrasound-assisted extraction UPE: Ultrahigh pressure extraction UV: Ultra-violet VHb: Vitreoscilla hemoglobin ZDS: -Carotene desaturase References Abdelazim K, Ghit A, Assal D, Dorra N, Noby N, Khattab SN, Hussein A (2023) Production and therapeutic use of astaxanthin in the nanotechnology era

Summary Keywords Alzheimer, dementia, genomics, integrative workflow, neurodegenerative diseases, precision medicine Citation Perezcano C and Prez-Coria M (2026) An integrative neurogenomics workflow for precision medicine in neurodegenerative disorders
Overall, this work proposed a convenient, safe, and effective rectal drug delivery strategy, providing a new candidate for the prevention and treatment of radiation-induced proctitis, and also providing a reference for the design of multifunctional local delivery systems in radiation-associated tissue injury