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In wing imaginal discs, cells surviving apoptotic insults acquire transient resistance to subsequent cell death, a phenomenon termed the Mahakali effect 65

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However, it has been reported that chicken DT40 cells lacking ADH5 can grow normally, and their sensitivity to exogenous formaldehyde is not different from wild-type cells [12]

Stress, environmental pollution, illness, inflammation, or an unbalanced diet can also increase the consumption of glutathione in cells