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CrossRef Glucagon-like peptide-1 receptor agonists reduce major adverse cardiovascular events and worsening heart failure in patients with heart failure: an umbrella meta-analysis Changxin Sun, Chuchuan Meng, Yongfang Yuan, Lanqing Hu, Xiaoya Li, Min Wu, Longtao Liu BMC Endocrine Disorders.2026;[Epub] CrossRef Collective exerkines mediate physical activity mitigating new-onset heart failure risk in older adults with prediabetes or diabetes: a community-based longitudinal cohort study Weike Liu, Luxiang Shang, Peilin Li, Yanli Yao, Haipeng Yin, Hua Zhang, Zhendong Liu, Yuqi Guo Cardiovascular Diabetology.2026;[Epub] CrossRef Glucose deprivation impairs lipid tolerance related to mitophagy disorder in cardiomyocytes Lishan Huang, Cuihua Huang, Zhiwen Xiao, Xin Chen, Menglan Zhan, Shuang Yao, Shuaijun Zhu, Zhou Chen, Libin Liu Molecular and Cellular Endocrinology.2026

doi: 10.1002/jcb.26234

For hyperopic patients this myopic shift temporarily causes an improvement in their near visual acuity, a phenomenon that is often called second sight. This increase in refractive power is associated with hardening of the lens nucleus

Ceramide accumulation can lead to mitochondrial and membrane permeabilization, triggering the release of cytochrome c into the cytoplasm favoring caspase-3-dependent apoptosis

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Therefore, NAD+ acts as an oxidizing agent (electron acceptor) in this context