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Medically Reviewed By: Karla K

Additional modifications were produced to improve the original discovery, of which four emerged as most logical candidates for drug development, including GHRP-6 (His-D-Trp-Ala-Trp-D-Phe-Lys-NH 2 ), Hexarelin (His-D-Mrp-Ala-Trp-D-Phe- Lys-NH 2 ), GHRP-2 (D-Ala-D--Nal-Ala-Trp-D-Phe-Lys) or pralmorelin which was most potent, and ipamorelin (Aib-His- D-2-Nal-D-Phe-Lys-NH 2 ) which persisted in the circulation longer than the other GHRPs 3

However, when compared with HGH, Sermorelin-Ipamorelin-CJC1295 has several important advantages: Genetically engineered HGH can cost more than $1,500 per month

Research Highlights No peer-reviewed studies published as of June 2025

suggests that they may exert a chain of intracellular cascades and events in somatotrophs by interacting with these receptors

Bone Density and Protecting Against Breakdown In animal studies, Ipamorelin prevented bone loss caused by high levels of corticosteroids (stress hormones)