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Honjo S, Ajani JA, Scott AW, Chen Q, Skinner HD, Stroehlein J, Johnson RL, Song S

Guenther, M.G

Cynaroside is one of the most common natural and safe bioactive substances and has attracted wide attention for its various biological functions such as anti-oxidation, antibacterial, anti-inflammatory, antiviral, anti-cancer and regulation of lipid metabolism (Bouyahya et al., 2023)

However, it is still unclear if GSH is involved in this protection under hypoxia

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Studies have shown that in breast cancer, lncRNA DILA1 directly binds to cyclin D1, preventing its phosphorylation at the Thr286 site, thereby inhibiting its degradation and increasing the proliferation of breast cancer cells and promoting resistance to tamoxifen