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Using Primes suite of biochemical and targeted sequencing assays, initial studies detected no off-target editing in human hepatocytes

Translating daily COVID-19 screening into a simple glucose test: a proof of concept study

A deep understanding of the chemical classification of these compounds not only aids in elucidating their pharmacological mechanisms but also provides a theoretical basis for predicting their pharmacokinetic behaviors (e.g., membrane permeability, metabolic stability) and potential clinical translation barriers

High local potency Reported ~10-fold more potent than intact IGF-1 in cell culture because it escapes IGF-binding-protein sequestration

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Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1