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38 During aging, elevated mtDNA mutations and impaired protein homeostasis synergistically induce excessive reactive oxygen species (ROS) production, resulting in oxidative stress and mitochondrial autophagy impairment, eventually perpetuating a vicious cycle of mitochondrial dysfunction

The epigenetic regulatory roles of curcumin include the inhibition of DNA methyltransferases (DNMTs), regulation of histone modifications via the regulation of histone acetyltransferases (HATs) and histone deacetylases (HDACs), regulation of microRNAs (miRNA), action as a DNA binding agent and interaction with transcription factors

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Premarital screening of 466 Mediterranean women for serum ferritin, vitamin B12, and folate concentrations

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This is because our liver, which metabolizes a majority of alcohol, can only do so at a certain rate