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When adverse effects occur, they may include mild skin reactions, gastrointestinal disturbance, or headache, typically following high-dose intramuscular injections rather than oral supplementation

Folate Receptor Alpha Autoantibodies: A more recent discovery of autoantibodies that target the Folate Receptor Alpha has been implicated in children with ASD

Some phase III trials with anti-endothelial compounds have been done but the results have not been encouraging indicating that this could eventually be a rather difficult problem to solve [80]

Directions: Inject subcutaneously once per day in the morning