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Bachta et al

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Norepinephrine and epinephrine are relatively small, highly polar molecules with primary amine groups that are fully protonated at physiological pH and show markedly negative distribution coefficients in aqueous buffer, indicating a strong preference for the aqueous phase 26,27,28,29,30

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These include inhibitors such as pyrrolidine dithiobarbamate (PDTC) (Wetli et al., 2006) and benzylisothiourea (Zhang et al., 2012)

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While direct contact between MenSCs and neurons inhibited neurite elongation, their secreted factorsincluding VEGF, HGF, and brain-derived neurotrophic factorpromoted axonal extension

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