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According to the NIH Office of Dietary Supplements, B12 plays a key role in: Making red blood cells and preventing megaloblastic anemia Maintaining healthy nerve function and the myelin sheath that protects nerves DNA synthesis Supporting brain function and preventing cognitive decline Converting food into energy (cellular metabolism) Because B12 is found almost exclusively in animal products meat, fish, dairy, and eggs certain groups of people are at much higher risk of deficiency than others

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These stresses include pathogens, elicitors, wounding, heat, low temperature, ultra-violet (UV) light, and ozone

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A well-executed prodrug strategy can effectively tackle various challenges in drug delivery, such as low solubility, instability, adverse effects, lack of specificity and poor cell uptake