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The tight junction protein cingulin regulates gene expression and rhoA signaling

EXS 124 NampoothiriM.ReddyN

Monks et al., 1996)

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Current treatments for glaucoma primarily aim to reduce IOP, which remains the only modifiable risk factor known to slow disease progression ( As advancements in understanding the pathophysiology of glaucoma continue, innovative therapeutic approaches are emerging to challenge the limitations of conventional treatments

236 Bacteria-derived lipopolysaccharide (which is a canonical PAMP often used to instigate reactive astrogliosis and microgliosis) act as agonists of TLR2 and 4