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Only the derivatives 35 and 37 , which bear a 2-aminoethyl-thionyl or a 2-chloroethyl-thionyl chain, respectively, showed a leishmanicidal response with a discrete IC 50 of 52.9 M and 27.9 M against promastigotes of L

Animal experiments were approved by the Wako Animal Experiment Committee in RIKEN (approval number: W2021-2-020(1))

After reconstitution, use solutions promptly under appropriate laboratory conditions and avoid repeated freezethaw cycles

181, 11512610.1111/j.1469-8137.2008.02653.x 4 FoyerC

During sepsis, immune cells such as neutrophils and macrophages are rapidly activated in response to microbial invasion, releasing large amounts of ROS, including superoxide anion (O 2 ), hydrogen peroxide (H 2 O 2 ), and hydroxyl radicals (OH ), as part of the hosts antimicrobial arsenal (Di Meo et al., 2016)

AVOID: Wheat germ, soybeans, vegetable oils, broccoli, Brussels sprouts, leafy greens, spinach, enriched flour, whole wheat, whole grain cereals, eggs, unrefined cold pressed crude vegetable oils, wheat germ and soybean oils, whole, raw or sprouted seeds, nuts and grains