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Increases in blood vessel constriction by COX-2 inhibition can also lead to the hypertension and renal failure seen in some studies of non-selective and COX-2 selective NSAIDs (Conaghan 2012)

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1 AHK-Cu and GHK-Cu are close chemical cousins (they differ in the first residue, alanine versus glycine), and they share the copper-binding motif that gives the family its character

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