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To illustrate, we can point to several double-blind, randomized controlled trials that otherwise failed to support its therapeutic potential for specific diseases

Other cells, such as epithelial cells, can transdifferentiate to CAFs via MMPs, ROS, and tumor-derived transforming growth factor- (TGF-) (76)

Also, many goat farmers give BoSe injections to adult and newborn goats as part of their regular goat health care

It summarizes key strategies for enhancing MSC adaptability and therapeutic efficacy and proposes standardized parameters for optimizing clinical applications, aiming to provide a theoretical basis and path support for advancing the clinical translation of stem cell therapy in intervertebral disc regeneration

doi: 10.1016/bs.apcsb.2019.02.001 283 HoheneggerMWaldhoerMBeindlWBingBKreimeyerANickelPet al