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Extracellular mechanical forces and ferroptosis in triple negative breast cancer (TNBC): targeting of aurora kinase A (AURKA)

Selumetinib, a MEK inhibitor, has shown promising results in clinical trials for treating NF1 patients with PN and was approved by the US Food and Drug Administration in April 2020 for pediatric NF1 patients aged at least 2 years who have symptomatic and inoperable PN

[DOI] [PubMed] [Google Scholar] 54.Anderson CP, Tsai JM, Meek WE, et al

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These discoveries have implications for treating particular diseases such as neurodegeneration and cancer, as well as general anti-aging efforts