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However, chronic exposure leads to irreversible neuronal loss and synaptic damage, manifesting as persistent memory, executive functioning, and decision-making deficits (North et al., 2013)

Liraglutide (LIRA), a glucagon-like peptide-1 (GLP-1) analog widely used in clinical applications, enhances the expression of Trx, Nrf2, and p-Erk1/2 to establish a protective effect against neurodegenerative diseases (Liu J

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4.5 Obesity-associated bronchial vascular airway remodeling in asthma Several key factors are implicated in the initiation and progression of bronchial vascular remodeling, including the pro-inflammatory cytokines (309311), angiopoietin (312, 313), and growth factors specifically VEGF (314316)

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