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Upon taking a history, the woman, who had not suffered from acne before, had recently received 3 weekly injections of vitamin B12, administered privately by a nurse in a local beauty salon without any screening for vitamin B12 deficiency

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In animal studies, it affects angiogenesis (blood vessel formation), collagen organization, and growth factor modulation through pathways including EGR-1 gene upregulation

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However, there is a growing body of evidence supporting the use of low-dose lithium medications and supplements for depression : Low-dose lithium medication (20 to 110mg) has been found to protect against future episodes of depression and suicidality in those who have had depression in the past