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High-pressure freezing and freeze substitution The general procedures for high-pressure freezing and freeze substitution were essentially performed as previously described 64

the hydrophobic tail preferentially interacts with the relatively non-polar component(s) while the hydrophilic head preferentially interacts with the relatively polar component(s)

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doi: 10.1093/glycob/cwz097 102 XieLChenWShuQXieWBianLDengGet al