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Xanthine oxidase inhibitor (XOI) therapy, particularly by use of allopurinol and febuxostat, is the primary approach used to treat hyperuricemia and thereby lower body urate stores [18]

In the study by Chen et al., melatonin protected hippocampal neurons from radiation-induced ferroptosis by activating the PKM2/NRF2/GPX4 signaling pathway, thereby reducing radiation-induced neuronal damage (142)

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Furthermore, copper peptide products, including a topical form of GHK-Cu, have been studied for their ability to promote hair growth