In clinical studies of diabetes with comorbid interstitial lung disease, tocilizumab effectively slowed the decline in diffusing capacity for carbon monoxide, potentially by neutralizing IL-6 and breaking the inflammatory cycle (Tanaka et al., 2018
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In NSCLC cells, reactive oxygen species (ROS)-mediated metabolic reprogramming leads to oxidative phosphorylation, which results in cisplatin resistance (19)
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Thiol peroxidases such as thioredoxin (Trx) peroxidases or peroxiredoxins (Prxs) and glutathione peroxidases (GPXs) are belongs to family of non-heme peroxidases
