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524 Additionally, Penkowa and Hidalgo demonstrated MT2 could become a prospective treatment candidate in multiple sclerosis, since it reduced cytokine expression in the CNS and prevent apoptotic neuronal death in an EAE model

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Defects in pyrimidine synthesis most commonly present as an increase in orotic acid in the urine

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Across all participants, the following reduced by a statistically significant amount: body weight decreased 10.9% (p 3 fold up-regulated (p 4 fold down-regulated in SP than NSP