foxo4 dri peptide senolytic mice 2023 FOXO4-DRI Senescent Cells | Their Role
Senescent Cells Their Role in Kidney Disease Kidney Coach Molecular modelling of the FOXO4 TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells ScienceDirect Peptide targeting senescent cells restores stamina, fur, and kidney function in old mice EurekAlert! The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv
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