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Eur J Drug Metab Pharmacokinet 47(1):118 Ghavami S, Kerkhoff C, Los M, Hashemi M, Sorg C, Karami-Tehrani F (2004) Mechanism of apoptosis induced by S100A8/A9 in colon cancer cell lines: the role of ROS and the effect of metal ions

doi: 10.1016/j.jep.2018.06.018

Based on the previous discussion, administration of antioxidants or Nrf2 inducers are potential viable therapies for viral-induced diseases, like respiratory infections and infections associated with reduced cellular antioxidant capacity (Komaravelli and Casola, 2014)

A growing literature suggests that IRwhich is ameliorated by boosting mitochondrial metabolism of LAC in rodent modelsis one of the proposed steps in the irreversible activation of the cascade leading from mood disorders to AD [73,74,75,76]