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Infertile patients with well-known pathologic features such as varicocele, leukospermia, hormonal abnormalities, and/or obstruction, the presence of cryptorchidism, vasectomy, abnormal liver function, cigarette smoking, alcohol consumption, anatomical disorders, Klinefelters syndrome, cancer, fever in the 90 days prior to sperm analysis, seminal sperm antibodies, were excluded from the study

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