chac1 glutathione CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers CHAC1 degradation of glutathione enhances
CHAC1 degradation of glutathione enhances cystine starvation induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2 eIF2 ATF4 pathway Oncotarget L 2 Hydroxyglutarate sensitizes ferroptosis through ATF3 CHAC1 mediated glutathione degradation in hepatocellular carcinoma Cell Death & Disease Identification of Juglone, a 'first in class' inhibitor of the human glutathione degrading enzyme, ChaC1, using yeast based high throughput screens bioRxiv A scheme of the mechanism of CHAC1 degradation of glutathione enhancing Download Scientific Diagram Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF CRE Regulatory Element ScienceDirect Calcium channel mutants rescue the effect of glutathione depletion. (A) Download Scientific Diagram
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