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Recommended investigations include: Full blood count with blood film examination Serum vitamin B12 level Serum folate (to exclude combined deficiency) Intrinsic factor antibodies Thyroid function tests (autoimmune association) Consider MMA and homocysteine if diagnosis uncertain and available Neurological examination should be performed in all patients, assessing for peripheral neuropathy, proprioception loss, and signs of subacute combined degeneration of the spinal cord

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Supplementation also reduced oxidative stress and doubled the effectiveness of Natural Killer immune cells

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Endocrine & HPA Axis Modulation: Studying the peptide's capacity to influence the hypothalamic-pituitary-adrenal (HPA) axis, specifically examining its suppressive effect on basal corticotropin (ACTH) and cortisol secretion