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174,175 In cases of vitamin B 12 depletion induced by HRA medications, levels of the vitamin have improved as a result of oral vitamin B 12 supplementation (as opposed to food source vitamin B 12 ingestion) as well as discontinuation of H2RA therapy

During this time, the patient may experience fatigue, weakness, and digestive issues

The most common diagnosis code is Z23 for encounter for immunization.

The methylation cycle supports functions such as: DNA synthesis Nervous system function Myelin production Homocysteine metabolism When vitamin B12 or folate levels are low, the body may have difficulty producing healthy red blood cells, which may contribute to macrocytic anemia

Serious (rare): Allergic reactions, rapid heartbeat, difficulty breathing

For instance, a patients follow-up visit for B12 re-evaluation is not recorded, causing issues with continuity of care