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Biochemical Pharmacology, 60(1), 19-29

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Thus, pharmacological TRP channel targeting may offer a future possibility to attenuate paclitaxel-induced mechanical and thermal hypersensitivity in clinical practice

A significant number of proteins involved in signaling have critical thiols (e.g., cell receptors, ubiquitinylation proteins, protein kinases, and some transcription factors)

Protein were then eluted by adding 20 l of IP lysis buffer (with protease inhibitors and phosphorylase inhibitors added) and 5 l 5SDS loading buffer, followed by 95 C for 5 min

These findings underscore the importance of baseline oxidative status, timing, and dose in determining the outcome of combined HBOT and NAC therapy