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Edited by Cold Spring Harbor Laboratory

Because the decline in autophagy function during aging has been linked to degenerative diseases in many organs, drugs targeting the process represent exciting candidates for prevention of cognitive decline and other degenerative diseases.

There were also no differences in PSI between women on and off oral contraceptives, suggesting: (1) no influence of menstrual cycle hormonal fluctuations on sulfonation, (2) no relevant inhibition of sulfonation of a single therapeutic dose of paracetamol by oral contraceptives, in contrast with previous in vitro and in vivo results 47,56

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