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However, the trend of reduced hyperlocomotion on days 7 and 14 and increased hypolocomotion on day 21 was observed in these combination groups as compared to their treatment alone

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Excellent dietary sources include : Meat and poultry : beef liver (particularly rich), lamb, chicken, and turkey Fish and seafood : salmon, trout, tuna, sardines, and shellfish (especially clams and mussels) Dairy products : milk, cheese, and yoghurt provide moderate amounts Eggs : particularly the yolk contains bioavailable B12 Fortified foods : breakfast cereals, plant-based milk alternatives, fortified yeast extracts (such as Marmite), and fortified nutritional yeast For individuals following plant-based diets, fortified foods and supplements become essential , as naturally occurring B12 in plant foods is negligible or in forms poorly utilised by humans

TICs are cycles created by reactions that carry fluxes even in the absence of nutrients essential for cellular growth and functionality

Zhu J, Hu Z, Luo Y, et al