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Studies have shown that it can resist the toxicity of APAP to hepatocytes by activating Nrf2

Sanchez, C., Gabay, O., Salvat, C., Henrotin, Y

Some individuals choose to use both NAC and glutathione together, taking NAC daily for consistent support while occasionally using liposomal glutathione for additional antioxidant benefits

Chapman LE, Darling AL, Brown JE

From a purely pharmacological perspective, the two molecules affect partially different receptors, which explains the theoretical interest of the question

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