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Xu X, Yin D, Ren H, Gao W, Li F, Sun D, Wu Y, Zhou S, Lyu L, Yang M, Xiong J (2018c) Selective NLRP3 inflammasome inhibitor reduces neuroinflammation and improves long-term neurological outcomes in a murine model of traumatic brain injury

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For example, Twist1-K150la simultaneously promotes its phosphorylation and nuclear translocation, consequently inducing the transcriptional activation of TGF1 in ECs

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However, their prominence has also contributed to an overemphasis on RCTs as the only true evidence of causation, sometimes at the expense of other valuable study designs