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10.1172/JCI73939 [DOI] [PMC free article] [PubMed] [Google Scholar] Kostopoulou E., Anagnostis P., Bosdou J

In another double-blind therapeutic trial, curcumin treatment shows encouraging results, demonstrating a slight slowdown in disease progression, improving aerobic metabolism and oxidative damage [50]

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The present study examined the morphological changes of KGN cells in the aforementioned groups using electron microscopy, measured the levels of oxidative stress [2,7-dichloro-dihydrofluorescein diacetate (DCFH-DA) assay of ROS, spectrophotometry of superoxide dismutase levels, ELISA of glutathione levels, spectrophotometry of malondialdehyde (MDA) levels], and examined cell apoptosis using flow cytometry and FSHR expression using western blotting to explore the effects of LC on the response of KGN cells to oxidative stress