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Indian J Dermatol Venereol Leprol 2016;82:262-72

Some major drawbacks associated with the clinical application of such NPs are their poor ability to cross the BBB and the inconsistent clinical efficacy of GDNF in PD treatment

NR is a nucleoside that incorporates a nicotinamide and a ribose (Lanska, 2012), available in certain foods (dairy products, fish, eggs, and vegetables) (Minto et al., 2017), nutritional supplements and fortified foods ( + by at least two types of metabolic pathway