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Brain 48 DaviesD.OlsonD.MeyerD.SchollJ.WattM.ManzerraP.et al (2016)

In drawing on studies that extend from clinical epidemiology, through genetics, pharmacotherapy and animal models, to cell biology and biochemistry, we have aimed to provide a comprehensible and accessible narrative, although this comes at the expense of a fully comprehensive and systematic (and inevitably longer) analysis

A prevailing mechanism of quinone-induced toxicity is that quinones as reactive electrophiles deplete GSH and covalently bind to proteins ( Rheum palmatum (Family Polygonaceae), Cassia occidentalis (Family Leguminosae), Morinda citrifolia (Family Rubiaceae), etc

doi: 10.4103/1673-5374.390969

If neurologic signs, perform magnetic resonance imaging (MRI) of the brain or computed tomography (CT) to rule out intracranial lesions, brain tumors or referral to a neurologist