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However, due to the limited sample size and lack of long-term follow-up in existing studies, we lack an in-depth understanding of the impact and incidence of this complication

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It promotes weight loss through multiple mechanisms: reducing appetite and food intake via central nervous system effects, slowing gastric emptying, and improving glycemic control through glucosedependent insulin secretion [1][3]

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[4] A separate 2024 randomized double-blind trial in people with HIV taking modern integrase-inhibitor regimens found that tesamorelin 2 mg daily significantly reduced both visceral and hepatic fat versus placebo, again without worsening glycemic control in that analysis