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It works by stimulating angiogenesis (the growth of new blood vessels), improving blood flow to injured areas and supporting the migration and proliferation of healing cells (Gwyer et al., 2019)

These modifications grant it pharmacokinetic properties absent in peptides oral bioavailability, protease resistance, and efficient blood-brain barrier penetration but also mean its metabolic fate and tissue distribution may differ substantially from peptide-class compounds

Fun fact: Mannitol can be found in foods as a sweetener

However, the adverse events were described as mainly transient and mild-to-moderate in severity

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