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[15] Is the Cori cycle a futile cycle

In their landmark 1973 paper, Lomo and Bliss recorded neuronal connection changes that were long-lasting and increased the strength of synaptic transmission, establishing the concept of LTP (Kandel et al., 1986), but in the 1990s pkc-mediated associative (conditioned) learning models were studied in both the marine sea snail Aplysia (Kruger et al., 1991) and the sea slug Hermissenda (Matzel et al., 1990

Therefore, these data provide direct evidence that mitochondrial oxidative catabolic activity causes ER stress