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NRF2 also controls the expression of glutathione S-transferases (GST) and glutathione peroxidases 2 (GPX2), which are enzymes known for detoxifying epoxide and H 2 O 2 , respectively

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Observe the area for 24 to 48 hours to ensure there is no adverse reaction, such as excessive redness, itching, or swelling

Studies have shown that the NLRP3 inflammasome is also involved in other skin diseases, such as psoriasis, urticaria, and bullous pemphigoid (179)

Another study [475] demonstrated that SCH-B reduced IL-17A production in CD4+ T cells by targeting STAT3 in vitro

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